Project outcomes

Peer review papers

1. Dusinska M, Tulinska J, EL Yamani N, Kuricova M, Liskova A, Rollerova E, Rundén-Pran E, Smolkova B. Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing? Food Chem Toxicol. 2017 Nov;109 (Pt 1):797-811. doi: 10.1016/j.fct.2017.08.030. Review.
2. Smolkova B, Dusinska M, Gabelova A. Nanomedicine and epigenome. Possible health risks. Food Chem Toxicol. 2017 Nov;109 (Pt 1):780-796. doi: 10.1016/j.fct.2017.07.020. Review.
3. Kontogianni G, Piroti G, Maglogiannis I, Chatziioannou A, Papadodima O. Dissecting the Mutational Landscape of Cutaneous Melanoma: An Omic Analysis Based on Patients from Greece. Cancers (Basel). 2018 Mar 29;10(4):96. doi: 10.3390/cancers10040096. PMID: 29596374; PMCID: PMC5923351.
4. Smolkova B, Horvathova Kajabova V, Zmetakova I, Kalinkova L, Czanner G, Markova A, Furdova A. Role of epigenetic deregulation in hematogenous dissemination of malignant uveal melanoma. Neoplasma. 2018 Nov 15;65(6):840-854. doi: 10.4149/neo_2018_180420N261. Epub 2018 Sep 4. PMID: 30334454.
5. Vlachavas EI, Pilalis E, Papadodima O, Koczan D, Willis S, Klippel S, Cheng CH, Pan L, Sachpekidis CH, Pintzas A, Gregoriou V, Dimitrakopoulou-Strauss A, Chatziioannou A. Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape, Comput Struct Biotechnol J, 17, 2019, 177-185.
6. Casals E, Gusta MF, Montana L, Mendoza M, Maiz N, Carreras E, Puntes V. Nanotechnology for Maternal Foetal Medicine. Int J Ped & Neo Heal. 2:5, 2018, 57-66.
7. Rucins M.; Dimitrijevs P.; Pajuste Kl.; Petrichenko O.; Jackevica L.; Gulbe A.; Kibilda S.; Smits K.; Plotniece M.; Tirzite D.; Pajuste K.; Sobolev A.; Liepins J.; Domracheva I.; Plotniece A. Contribution of molecular structure to self-assembling and biological properties of bifunctional lipid-like 4-(N-alkylpyridinium)-1,4-dihydropyridines. Pharmaceutics, 2019, 11(3), 115; https://doi.org/10.3390/pharmaceutics11030115
8. Zmetakova, I., Kalinkova, L., Smolkova, B., Horvathova Kajabova, V., Cierna, Z., Danihel, L., Bohac, M., Sedlackova, T., Minarik, G., Karaba, M., Benca, J., Cihova, M., Buocikova, V., Miklikova, S., Mego, M., & Fridrichova, I. (2019). A disintegrin and metalloprotease 23 hypermethylation predicts decreased disease-free survival in low-risk breast cancer patients. Cancer Science, 110(5), 1695–1704. https://doi.org/10.1111/cas.13985
9. Vekris*, A., Pilalis*, E., Chatziioannou, A., and Petry, K. G. (2019). A Computational Pipeline for the Extraction of Actionable Biological Information from NGS-Phage Display Experiments. Frontiers in Physiology 10, 1160. (*equal contribution)
10. Vlachavas, E., Pilalis, E., Papadodima, O., Koczan, D., Willis, S., Klippel, S., et al. (2019). Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape Computational and structural biotechnology journal 17, 177–185
11. Rucins M.; Pajuste Kl.; Sobolev A.; Plotniece M.; Pikun N.; Pajuste K.; Plotniece A. Data for the synthesis and characterisation of 2,6-di(bromomethyl)-3,5-bis(alkoxycarbonyl)-4-aryl-1,4-dihydropyridines as important intermediates for synthesis of amphiphilic 1,4-dihydropyridines. Data in Brief, 2020, 30, 105532; https://doi.org/10.1016/j.dib.2020.105532
12. Rucins M.; Smits R.; Sipola A.; Vigante B.; Domracheva I.; Turovska B.; Muhamadejev R.; Pajuste K.; Plotniece M.; Sobolev A.; Duburs G.; Plotniece A. Pleiotropic properties of amphiphilic dihydropyridines, dihydropyridones and aminovinylcarbonyl compounds. Oxidative Med. Cell. Longevity, 2020, Article ID 8413713, 17 pages; https://doi.org/10.1155/2020/8413713
13. Patsula V, Tulinska J, Trachtová Š, Kuricova M, Liskova A, Španová A, Ciampor F, Vavra I, Rittich B, Ursinyova M, Dusinska M, Ilavska S, Horvathova M, Masanova V, Uhnakova I, Horák D. Toxicity evaluation of monodisperse PEGylated magnetic nanoparticles for nanomedicine. Nanotoxicology. 2019 May;13(4):510-526. doi: 10.1080/17435390.2018.1555624. Epub 2019 Feb 1. PMID: 30704361.
14. Dusinska M, Mariussen E, Rundén-Pran E, Hudecova AM, Elje E, Kazimirova A, El Yamani N, Dommershausen N, Tharmann J, Fieblinger D, Herzberg F, Luch A, Haase A. In Vitro Approaches for Assessing the Genotoxicity of Nanomaterials. Methods Mol Biol. 2019;1894:83-122. doi: 10.1007/978-1-4939-8916-4_6. PMID: 30547457.
15. Buocikova V.; Rios-Mondragon I.; Pilalis E.; Chatziioannou A.; Miklikova S.; Mego M.; Pajuste K.; Rucins M.; El Yamani N.; Longhin E.M.; Sobolev A.; Freixanet M.; Puntes V.; Plotniece A.; Dusinska M.; Cimpan M.R.; Gabelova A.; Smolkova B. Epigenetics in BC Therapy—New Strategies and Future Nanomedicine Perspectives. Cancers, 2020, 12, 3622; https://doi.org/10.3390/cancers12123622
16. Yvonne Kohl, Elise Rundén-Pran, Espen Mariussen, Michelle Hesler, Naouale El Yamani, Eleonora Marta Longhin and Maria Dusinska
17. Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment—A Review, NANOMATERIALS 2020, 10, 1911; doi:10.3390/nano10101911
18. Binenbaum I, Atamni HA, Fotakis G, Kontogianni G, Koutsandreas T, Pilalis E, Mott R, Himmelbauer H, Iraqi FA, Chatziioannou AA. Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity. BMC Genomics. 2020 Nov 3;21(1):761. doi: 10.1186/s12864-020-07173-x. PMID: 33143653; PMCID: PMC7640698.
19. MIKLÍKOVÁ, Svetlana - MINÁRIK, Gabriel - SEDLACKOVA, T. - PLAVÁ, Jana - CIHOVÁ, Marína - JURIŠOVÁ, Silvia - KAĽAVSKÁ, Katarína - KARABA, Marián - BENCA, Juraj - SMOLKOVÁ, Božena - MEGO, Michal**. Inflammation-based scores increase the prognostic value of circulating tumour cells in primary BC. In Cancers, 2020, vol. 12, no. 5, art.no. 1134.
20. SMOLKOVÁ, Božena* - ČIERNA, Zuzana* - KAĽAVSKÁ, Katarína - MIKLÍKOVÁ, Svetlana - PLAVÁ, Jana - MINÁRIK, Gabriel - SEDLÁČKOVÁ, Tatiana - CHOLUJOVÁ, Dana - GRONESOVÁ, Paulína - CIHOVÁ, Marína - MAJEROVÁ, Karolína - KARABA, Marián - BENCA, Juraj - PINDAK, D. - MARDIAK, Jozef - MEGO, Michal**. Increased stromal infiltrating lymphocytes are associated with the risk of disease progression in mesenchymal circulating tumour cell-positive primary BC patients. In International Journal of Molecular Sciences, 2020, vol. 21, no. 24, art. no. 9460.
21. Mego M, Kalavska K, Karaba M, Minarik G, Benca J, Sedlackova T, Gronesova P, Cholujova D, Pindak D, Mardiak J, Celec P. Plasma Nucleosomes in Primary Breast Cancer. Cancers (Basel). 2020 Sep 10;12(9):2587. doi: 10.3390/cancers12092587. PMID: 32927889; PMCID: PMC7563724.
22. Cierna, Z., Smolkova, B., Cholujova, D., Gronesova, P., Miklikova, S., Cihova, M., Plava, J., & Mego, M. (2021). Decreased levels of circulating cytokines VEGF, TNF-β and IL-15 indicate PD-L1 overexpression in tumours of primary BC patients. Scientific reports, 11(1), 1294. https://doi.org/10.1038/s41598-020-80351-9
23. Kohl Y, Biehl M, Spring S, Hesler M, Ogourtsov V, Todorovic M, Owen J, Elje E, Kopecka K, Moriones OH, Bastús NG, Simon P, Dubaj T, Rundén-Pran E, Puntes V, William N, von Briesen H, Wagner S, Kapur N, Mariussen E, Nelson A, Gabelova A, Dusinska M, Velten T, Knoll T. Microfluidic In Vitro Platform for (Nano)Safety and (Nano)Drug Efficiency Screening. Small. 2021 Apr;17(15):e2006012. doi: 10.1002/smll.202006012. Epub 2021 Jan 18. PMID: 33458959.
24. Decitabine Potentiates Efficacy of Doxorubicin in a Preclinical Trastuzumab-Resistant HER2-Positive Breast Cancer Models. Verona Buocikova1, Eleonora Marta Longhin2, Eleftherios Pilalis 3,4, Chara Mastrokalou,4, Svetlana Miklikova1, Marina Cihova1, Alexandra Poturnayova5, Katarina Mackova5, Andrea Babelova1, Lenka Trnkova1, Naouale El Yamani2, Congying Zheng6, Ivan Rios-Mondragon7, Martina Labudova8, Lucia Csaderova8, Kristina Mikus Kuracinova7, Peter Makovicky1, Lucia Kucerova1, Miroslava Matuskova1, Mihaela Roxana Cimpan7, Maria Dusinska2, Pavel Babal9, Aristotelis Chatziioannou3,4, Alena Gabelova1, Elise Rundén-Pran2, Bozena Smolkova1* Submitted.